STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DcpPeptidyl-dipeptidase Dcp; COG0339 Zn-dependent oligopeptidases. (684 aa)    
Predicted Functional Partners:
gltX
COG0008 Glutamyl- and glutaminyl-tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
  
 0.625
RAM_23610
Phosphoglycerate mutase; COG0406 Fructose-2,6-bisphosphatase.
     
 0.569
RAM_11860
YbaK-like protein.
 
      0.528
uppP-2
Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
       0.467
Hmd-3
COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
       0.449
RAM_12210
Prolyl oligopeptidase; COG1505 Serine proteases of the peptidase family S9A.
  
 
 0.445
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
   
 
 0.432
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity.
  
  
 0.419
RAM_34185
Probable chaperone protein; COG0326 Molecular chaperone, HSP90 family.
  
  
 0.419
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.