STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_23920DNA gyrase inhibitor. (161 aa)    
Predicted Functional Partners:
RAM_23930
Hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
     0.802
RAM_23925
COG3795 Uncharacterized protein conserved in bacteria.
       0.773
RpoE-34
COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.
       0.773
RAM_23940
COG1309 Transcriptional regulator.
       0.723
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.660
RAM_23945
COG2124 Cytochrome P450.
       0.516
RAM_39550
Hypothetical protein.
  
     0.499
FtsK-4
Cell division FtsK/SpoIIIE; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins.
  
     0.442
RAM_01855
TraJ; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins.
  
     0.441
RAM_34850
COG1396 Predicted transcriptional regulators.
  
     0.411
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.