STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_24070Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (185 aa)    
Predicted Functional Partners:
nnrD
Ribokinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NA [...]
  
 0.682
RAM_24075
COG1349 Transcriptional regulators of sugar metabolism.
       0.568
RAM_06055
COG0557 Exoribonuclease R.
  
 0.494
RAM_05630
COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
  
 0.473
RAM_07850
COG0513 Superfamily II DNA and RNA helicases.
  
 0.473
RAM_10450
COG0513 Superfamily II DNA and RNA helicases.
  
 0.473
RAM_14015
Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
  0.418
RAM_29560
Beta-lactamase class B; COG0491 Zn-dependent hydrolases, including glyoxylases.
 
 
   0.412
RAM_28045
Beta-lactamase class B; COG0491 Zn-dependent hydrolases, including glyoxylases.
 
 
   0.403
RAM_20065
Formyl transferase-like protein; COG0223 Methionyl-tRNA formyltransferase.
 
 0.402
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.