STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_24075COG1349 Transcriptional regulators of sugar metabolism. (249 aa)    
Predicted Functional Partners:
FruA
PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB.
 
  
 0.755
FruK
1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.714
LacC
Tagatose 6-phosphate kinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB).
 
  
 0.693
FruK-2
1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB).
 
  
 0.570
RAM_24070
Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
       0.568
FruB
PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
 
  
 0.455
GlpA-3
FAD dependent oxidoreductase; COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.451
GlpA-2
COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.430
GlpA
COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.427
ManZ
Mannose/fructose-specific IIC/D component of PTS system; COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC.
 
  
 0.414
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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