STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_24175COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding). (168 aa)    
Predicted Functional Partners:
RAM_24180
COG4865 Glutamate mutase epsilon subunit.
 
  0.997
RAM_24425
COG4865 Glutamate mutase epsilon subunit.
 
  0.977
RAM_24190
COG0069 Glutamate synthase domain 2.
 
     0.928
RAM_24420
COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).
  
  
0.918
AsnS
COG0017 Aspartyl/asparaginyl-tRNA synthetases.
 
     0.847
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.834
RAM_06825
COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.814
RAM_25280
COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.814
PutA
COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
     
 0.802
glsA
COG2066 Glutaminase; Belongs to the glutaminase family.
    
  0.801
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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