STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_24285Kinase; COG4542 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase. (324 aa)    
Predicted Functional Partners:
CobI
COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.881
RAM_24275
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
       0.777
RAM_24280
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
       0.777
RAM_24290
COG0477 Permeases of the major facilitator superfamily.
       0.773
RAM_24230
Argininosuccinate lyase; COG0439 Biotin carboxylase.
 
   
 0.728
MbtH-3
MbtH protein; COG3251 Uncharacterized protein conserved in bacteria.
       0.642
RAM_24240
Cystathionine beta-synthase/cysteine synthase; COG0031 Cysteine synthase.
 
   
 0.631
CobM
COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.629
CysG
uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain).
 
   
 0.618
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.609
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.