STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lrp-5COG1522 Transcriptional regulators. (151 aa)    
Predicted Functional Partners:
RAM_24805
X-Pro dipeptidase; COG0006 Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family.
   
 
 0.892
AsnC-4
COG1522 Transcriptional regulators.
  
     0.770
RAM_14595
COG1316 Transcriptional regulator.
   
    0.675
RAM_24790
Hypothetical protein.
       0.638
RAM_24795
Hypothetical protein.
       0.638
RAM_24810
COG0258 5'-3' exonuclease (including N-terminal domain of PolI).
       0.595
RAM_29585
ATPase; COG3903 Predicted ATPase.
   
    0.577
IciA
Chromosome replication initiation inhibitor protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
   
  
 0.572
RAM_11195
Signal transduction protein; COG0784 FOG: CheY-like receiver.
   
    0.549
cobB
SIR2 family NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
  
    0.536
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: medium (66%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.