STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uspEUniversal stress protein UspE; With UspC and UspD is involved in resistance to UV irradiation; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)    
Predicted Functional Partners:
fnr
Transcriptional regulator; It is involved in the activation of genes necessary for anaerobic respiration. It probably also activates genes involved in the production of virulence factors.
  
 0.909
AMQ93249.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.732
trxA
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
   
 
 0.672
yihI
Aminotransferase; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.671
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
      
 0.643
AMQ94530.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.640
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
 
  
 0.635
metJ
Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
    0.616
yejK
Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.600
AMQ93843.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.599
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.