Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMQ93108.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)    
Predicted Functional Partners:
AMQ93110.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.976
AMQ93109.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.941
AMQ94436.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.838
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
    
 0.633
narL
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.574
AMQ93112.1
Pesticidal protein Cry1Aa; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.554
AMQ93529.1
Adhesin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.539
AMQ93111.1
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.509
hfq
RNA-binding protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
     
 0.474
dksA
Molecular chaperone DnaK; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.
  
  
 0.473
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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