Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
znuCMn2+/Zn2+ABC transporter ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (257 aa)    
Predicted Functional Partners:
znuB
High-affinity zinc transporter membrane component; Involved in transport of zinc(II) with ZnuA and C; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
znuA
Zinc ABC transporter substrate-binding protein; Involved in transport of zinc(II) with ZnuA and C; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
afeD
Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.857
afeC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.857
afeA
Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.738
lptG
LPS export ABC transporter permease LptG; With LptABCF is involved in the transport of lipopolysaccharides; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.678
oppD
Oligopeptide transporter ATP-binding component; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.
 
     
0.648
mepM
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.558
AMQ94905.1
Peptide ABC transporter ATP-binding protein; Involved in resistance to antimibial peptides; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.
 
     
0.466
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
      
 0.407
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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