Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMQ93294.1Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)    
Predicted Functional Partners:
msrAB
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
   
 0.956
AMQ93290.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.896
AMQ93292.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.887
AMQ93291.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.876
AMQ93293.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     0.861
AMQ93295.1
Cytochrome C biogenesis protein CcsB; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.784
dsbD
Thiol:disulfide interchange protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
  
 
 0.738
AMQ93356.1
Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.707
AMQ93357.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.684
AMQ93288.1
Iron permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.683
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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