Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nfsANADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flavin oxidoreductase frp family. (244 aa)    
Predicted Functional Partners:
rimK
Ribosomal protein S6 modification protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RimK family.
  
  
 0.864
cls
Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
      
 0.678
AMQ93443.1
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.538
AMQ93029.1
Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.525
lon
DNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
      
 0.460
AMQ93333.1
Ribosomal protein S12 methylthiotransferase accessory factor YcaO; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.457
AMQ93778.1
NAD(P)H nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.423
AMQ95097.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.409
gloA
Glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
    0.406
AMQ93062.1
2-acyl-glycerophospho-ethanolamine acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.401
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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