STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMQ93456.1PTS ascorbate-specific subunit IIBC; Functions with enzymes IIB and IIC, enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; Derived by automated computational analysis using gene prediction method: Protein Homology. (590 aa)    
Predicted Functional Partners:
AMQ93457.1
PTS ascorbate-specific transporter subunit IIA; Involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.995
ulaG
Ascorbate 6-phosphate lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.992
AMQ94764.1
PTS mannitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.979
AMQ94765.1
PTS beta-glucoside transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.939
ulaD
Catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.928
ptsH
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.912
AMQ93453.1
L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.890
gatZ
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.834
araD
Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.646
ptsN
PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.577
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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