STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tldDProtein TldD; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)    
Predicted Functional Partners:
pmbA
Protein PmbA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.817
sppA
Signal peptide peptidase SppA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.620
deoR
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.618
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
    0.599
AMQ93463.1
Alpha-2-macroglobulin; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.584
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
  
 0.561
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
     
 0.542
AMQ93465.1
Pyrophosphorylase ModD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family.
       0.407
AMQ93466.1
Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.407
AMQ93467.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.407
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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