| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMQ93546.1 | rdgC | ACT75_02930 | ACT75_02935 | Pyrroline-5-carboxylate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | 0.557 |
| AMQ93546.1 | xerD | ACT75_02930 | ACT75_02925 | Pyrroline-5-carboxylate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.775 |
| djlA | radA | ACT75_05265 | ACT75_02005 | Molecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.622 |
| djlA | rdgC | ACT75_05265 | ACT75_02935 | Molecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | 0.614 |
| djlA | recJ | ACT75_05265 | ACT75_01085 | Molecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.653 |
| parC | rdgC | ACT75_01825 | ACT75_02935 | DNA topoisomerase IV; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | 0.501 |
| radA | djlA | ACT75_02005 | ACT75_05265 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | Molecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 0.622 |
| radA | rdgC | ACT75_02005 | ACT75_02935 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | 0.560 |
| radA | recJ | ACT75_02005 | ACT75_01085 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.642 |
| rdgC | AMQ93546.1 | ACT75_02935 | ACT75_02930 | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | Pyrroline-5-carboxylate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.557 |
| rdgC | djlA | ACT75_02935 | ACT75_05265 | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | Molecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 0.614 |
| rdgC | parC | ACT75_02935 | ACT75_01825 | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | DNA topoisomerase IV; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.501 |
| rdgC | radA | ACT75_02935 | ACT75_02005 | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.560 |
| rdgC | recJ | ACT75_02935 | ACT75_01085 | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.621 |
| rdgC | rpoA | ACT75_02935 | ACT75_03985 | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.525 |
| rdgC | ruvA | ACT75_02935 | ACT75_09465 | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.501 |
| rdgC | sbcB | ACT75_02935 | ACT75_00180 | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.533 |
| rdgC | tusC | ACT75_02935 | ACT75_05960 | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | Sulfur relay protein TusC/DsrF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family. | 0.494 |
| rdgC | xerD | ACT75_02935 | ACT75_02925 | Recombination-associated protein RdgC; May be involved in recombination. Belongs to the RdgC family. | Recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.633 |
| recJ | djlA | ACT75_01085 | ACT75_05265 | 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 0.653 |