STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrfACytochrome C nitrite reductase; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (510 aa)    
Predicted Functional Partners:
nrfD
Nitrite reductase; Membrane protein, may be involved in the transfer of electrons from quinones to c-type cytochromes; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.943
napA
Nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
   
 
 0.917
AMQ94196.1
Diacylglycerol kinase; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
  
 
 0.917
glnA
Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.902
AMQ94588.1
Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.902
nrfC
Nitrite reductase; 4Fe4S subunit; may be involved in the transfer of electrons from quinones to the c-type cytochromes; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.879
nrfB
Cysteine dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.849
narL
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.627
AMQ93088.1
Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TorC/TorY family.
  
 
 0.625
AMQ94197.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.625
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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