STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
narLTwo-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)    
Predicted Functional Partners:
AMQ94436.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
narQ
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.997
AMQ93913.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the adenylyl cyclase class-1 family.
     
 0.781
nrfA
Cytochrome C nitrite reductase; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family.
      
 0.627
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
      
 0.610
crp
Cyclic AMP receptor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.604
AMQ93915.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.593
cpxA
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.592
arcA
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.574
AMQ93108.1
Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.557
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.