STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uspAUniversal stress protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family. (142 aa)    
Predicted Functional Partners:
mukB
Cell division protein MukB; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.
  
     0.766
AMQ93909.1
Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.727
AMQ95136.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.726
AMQ93334.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.699
ftsN
Cell division protein FtsN; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.698
holA
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.650
AMQ94285.1
C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.642
lapA
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.634
djlA
Molecular chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
  
   
 0.633
recJ
5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.592
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.