STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMQ94020.1Acriflavin resistance protein AcrA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (371 aa)    
Predicted Functional Partners:
macB
Macrolide transporter; Part of the tripartite efflux system MacAB-TdeA. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
 
 
 0.999
AMQ94023.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.900
AMQ93985.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.880
AMQ93986.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
     0.702
tdeA
Hypothetical protein; Required for secretion of the LtxA leukotoxin and resistance to various antimicrobial compounds.
 
 
 0.631
AMQ95096.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
 
 
 0.630
AMQ93291.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.575
AMQ94019.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.550
AMQ94018.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.547
AMQ94911.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.543
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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