Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMQ94073.1Glutamate 5-kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (59 aa)    
Predicted Functional Partners:
AMQ94074.1
Glutamate 5-kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     0.992
AMQ93497.1
Glutamate-5-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.902
thrA
Aspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.562
AMQ94071.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.532
AMQ94072.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.532
AMQ93546.1
Pyrroline-5-carboxylate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.528
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.515
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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