Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
slyXSlyX protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SlyX family. (73 aa)    
Predicted Functional Partners:
dsbB
Disulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
  
  
 0.767
sprT
Zn-dependent metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SprT family.
  
     0.692
nhaB
Sodium:proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
  
   
 0.690
fadR
Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism.
   
  
 0.683
tusD
Sulfur relay protein TusD; In Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.599
tusC
Sulfur relay protein TusC/DsrF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family.
 
    0.598
lapA
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.595
AMQ94110.1
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.593
brnQ
Branched-chain amino acid transporter; Component of the transport system for branched-chain amino acids.
  
   
 0.593
AMQ95138.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0352 family.
  
   
 0.564
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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