STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slyXSlyX protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SlyX family. (73 aa)    
Predicted Functional Partners:
dsbB
Disulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
  
  
 0.714
sprT
Zn-dependent metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SprT family.
  
     0.692
brnQ
Branched-chain amino acid transporter; Component of the transport system for branched-chain amino acids.
  
   
 0.669
nhaB
Sodium:proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
  
   
 0.658
fadR
Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism.
   
  
 0.620
tusC
Sulfur relay protein TusC/DsrF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family.
 
     0.606
lapA
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.595
tusD
Sulfur relay protein TusD; In Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.595
AMQ94110.1
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.571
yihI
Aminotransferase; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.546
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.