Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMQ94127.1NmrA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)    
Predicted Functional Partners:
AMQ95036.1
NAD(P)H oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.904
AMQ94128.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.831
napG
Quinol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.773
AMQ94831.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.773
AMQ93147.1
Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M16 family.
   
 
 0.722
AMQ94460.1
Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
   
 
 0.704
AMQ93823.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.648
frdA
Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.626
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.613
AMQ94221.1
Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.613
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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