Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
xylFD-xylose transporter subunit XylF; Periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)    
Predicted Functional Partners:
AMQ94182.1
Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.
 
 0.991
xylG
Xylose transporter; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.
 
 0.981
xylA
Xylose isomerase; Catalyzes the interconversion of D-xylose to D-xylulose; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the xylose isomerase family.
 
  
 0.748
AMQ94179.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.636
AMQ94545.1
Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.558
AMQ94335.1
Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.513
nhaC
Sodium:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.430
AMQ94181.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.430
AMQ94958.1
Glycerate dehydrogenase; Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
      
 0.419
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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