STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgaAPoly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA; Derived by automated computational analysis using gene prediction method: Protein Homology. (795 aa)    
Predicted Functional Partners:
pgaC
Poly-beta-1,6 N-acetyl-D-glucosamine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.912
pgaB
poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.774
hmsD
HmsD; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.726
envC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.670
wbaP
UDP-phosphate galactose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.449
csrA
Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
      
 0.407
deoD
Purine nucleoside phosphorylase; Catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.405
AMQ94436.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.401
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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