STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
citFcitrate-ACP transferase, the alpha subunit catalyzes the formation of (3S)-citryl-CoA from acetyl-CoA and citrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)    
Predicted Functional Partners:
citE
Citrate lyase subunit beta; citryl-ACP lyase; catalyzes the formation of acetate and oxaloacetate from citrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.997
citG
2-(5'-triphosphoribosyl)-3'-dephospho CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.997
citD
Citrate lyase subunit gamma; Covalent carrier of the coenzyme of citrate lyase.
 
 
 0.996
citC
Citrate (pro-3S)-lyase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
 
  
 0.979
nanA
N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
   
    0.657
dapA
4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
   
    0.657
oadA
Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.512
AMQ94428.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.491
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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