Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMQ94541.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)    
Predicted Functional Partners:
AMQ94542.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.726
AMQ94101.1
Patatin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.646
nanM
N-acetylneuraminic acid mutarotase; Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta- anomer, accelerating the equilibrium between the alpha- and beta- anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses; Belongs to the NanM family.
  
     0.610
AMQ94543.1
Phospholipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.598
AMQ94198.1
Catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.567
AMQ94948.1
PTS glucose transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.567
AMQ93035.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.532
AMQ93485.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.508
AMQ93290.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.468
AMQ94540.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.448
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.