Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMQ94545.1Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)    
Predicted Functional Partners:
AMQ94546.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.993
AMQ94544.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family.
  
 0.942
AMQ94547.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.925
rraA
Ribonuclease E activity regulator RraA; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
 
      0.679
citE
Citrate lyase subunit beta; citryl-ACP lyase; catalyzes the formation of acetate and oxaloacetate from citrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
   
    0.657
gatZ
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.641
gntR
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.631
xylF
D-xylose transporter subunit XylF; Periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.558
AMQ94523.1
PTS fructose transporter subunit IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.552
AMQ94542.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.548
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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