STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
afeAIron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family. (293 aa)    
Predicted Functional Partners:
afeD
Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
afeC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
afeB
Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
znuB
High-affinity zinc transporter membrane component; Involved in transport of zinc(II) with ZnuA and C; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.874
znuC
Mn2+/Zn2+ABC transporter ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
  
  
 0.753
metC
Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.630
cyaY
Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
      
 0.614
AMQ93288.1
Iron permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.611
rpsN
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
  
 0.544
AMQ94779.1
Sulfur relay protein TusE; Part of a sulfur-relay system.
       0.531
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.