Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMQ94815.1Carboxy-terminal protease; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. (685 aa)    
Predicted Functional Partners:
nlpI
Lipoprotein NlpI-like protein; May be involved in cell division.
  
 
 
 0.784
proQ
ABC transporter substrate-binding protein; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.
  
  
 0.715
AMQ94816.1
L,D-transpeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.598
AMQ94514.1
NrfG protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.568
AMQ94892.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.535
AMQ95094.1
Endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.535
envC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.511
pgaA
Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.483
rseP
Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.465
AMQ94812.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.431
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
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