STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMQ94928.1MazF family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa)    
Predicted Functional Partners:
AMQ94927.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.915
AMQ93475.1
Antitoxin MazE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.592
vppA
Virulence protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.570
AMQ94930.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.548
cdtA
Cytochrome C oxidase subunit I; CDTs are cytotoxins which induce host cell distension, growth arrest in G2/M phase, nucleus swelling, and chromatin fragmentation in HeLa cells.
       0.548
cdtB
Cytolethal distending toxin subunit CdtB; Cdt from Campylobacter forms the A subunit (CdtB) that is delivered into host cells by the heterologous B subnit (CdtA/C); in Salmonella, CdtB alone is encoded; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.524
cdtC
Cytochrome C oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.514
AMQ93363.1
Addiction module toxin RelE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.446
AMQ94128.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.403
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.