STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
malKMaltose/maltodextrin transporter ATP-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (372 aa)    
Predicted Functional Partners:
malF
With MalKGE is involved in maltose transport into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
malE
Sugar ABC transporter substrate-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.
 
 0.999
malG
Maltose transporter permease; With MalKFE is involved in the transport of maltose into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
lamB
Maltoporin; Porin involved in the transport of maltose and maltodextrins; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.916
AMQ94905.1
Peptide ABC transporter ATP-binding protein; Involved in resistance to antimibial peptides; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.
 
    
0.905
modB
Molybdenum ABC transporter permease; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
      0.884
malM
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.802
malS
Alpha-amylase; Periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.775
AMQ93263.1
Spermidine/putrescine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.753
msbA
Lipid transporter ATP-binding/permease; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
 
    
0.679
Your Current Organism:
Aggregatibacter actinomycetemcomitans
NCBI taxonomy Id: 714
Other names: A. actinomycetemcomitans, ATCC 33384, Actinobacillus (Haemophilus) actinomycetemcomitans, Actinobacillus actinomycetemcomitans, Bacterium acetinomycetum comitans, Bacterium actinomycetem comitans, Bacterium comitans, CCUG 13227, CIP 52.106, DSM 8324, Haemophilus actinomycetemcomitans, Haemophilus actinomyceticomitans, NCTC 9710
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.