| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hybG | hycE | ACT75_11430 | ACT75_10030 | Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.694 |
| hybG | hypA | ACT75_11430 | ACT75_01985 | Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.735 |
| hybG | hypB | ACT75_11430 | ACT75_01045 | Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.956 |
| hybG | hypD | ACT75_11430 | ACT75_01040 | Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase isoenzyme formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | 0.988 |
| hybG | hypE | ACT75_11430 | ACT75_01035 | Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase isoenzymes formation protein; involved in the formation of the cyanate group of the large subunit of the hydrogenase; catalyzes the formation of thiocyanate from thiocarbamate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.971 |
| hybG | hypF | ACT75_11430 | ACT75_10065 | Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl phosphate phosphatase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.876 |
| hycE | hybG | ACT75_10030 | ACT75_11430 | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.694 |
| hycE | hypA | ACT75_10030 | ACT75_01985 | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.768 |
| hycE | hypB | ACT75_10030 | ACT75_01045 | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| hycE | hypD | ACT75_10030 | ACT75_01040 | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase isoenzyme formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | 0.556 |
| hycE | hypE | ACT75_10030 | ACT75_01035 | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase isoenzymes formation protein; involved in the formation of the cyanate group of the large subunit of the hydrogenase; catalyzes the formation of thiocyanate from thiocarbamate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.575 |
| hycE | hypF | ACT75_10030 | ACT75_10065 | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl phosphate phosphatase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.703 |
| hypA | hybG | ACT75_01985 | ACT75_11430 | Hypothetical protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.735 |
| hypA | hycE | ACT75_01985 | ACT75_10030 | Hypothetical protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.768 |
| hypA | hypB | ACT75_01985 | ACT75_01045 | Hypothetical protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.939 |
| hypA | hypD | ACT75_01985 | ACT75_01040 | Hypothetical protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase isoenzyme formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | 0.857 |
| hypA | hypE | ACT75_01985 | ACT75_01035 | Hypothetical protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase isoenzymes formation protein; involved in the formation of the cyanate group of the large subunit of the hydrogenase; catalyzes the formation of thiocyanate from thiocarbamate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.848 |
| hypA | hypF | ACT75_01985 | ACT75_10065 | Hypothetical protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Carbamoyl phosphate phosphatase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.825 |
| hypB | hybG | ACT75_01045 | ACT75_11430 | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.956 |
| hypB | hycE | ACT75_01045 | ACT75_10030 | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |