STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HI_1427Predicted coding region HI1427; Hypothetical protein; identified by GeneMark; putative. (278 aa)    
Predicted Functional Partners:
HI_0552
Predicted coding region HI0552; Hypothetical protein; identified by GeneMark; putative.
  
     0.774
HI_0974
Predicted coding region HI0974; Hypothetical protein; identified by GeneMark; putative.
  
     0.773
tbpA
Transferrin-binding protein 1 precursor (tbp1); Acts as a transferrin receptor and is required for transferrin utilization; Belongs to the TonB-dependent receptor family.
  
    0.749
tehB
Tellurite resistance protein (tehB); Probable S-adenosyl-L-methionine-dependent methyltransferase. Plays a role in both resistance to oxidative damage and heme uptake/utilization. Also protects H.influenzae from tellurite exposure in vitro; however, since H.influenzae grows only in humans, it is unlikely to encounter tellurite in its natural environment, and it is thus probable that tellurite resistance does not represent a biologically relevant role of TehB (By similarity); Belongs to the TehB family.
  
     0.726
HI_1376
Predicted coding region HI1376; Hypothetical protein; identified by GeneMark; putative.
  
     0.681
HI_1621
Conserved hypothetical protein; May be involved in metal transport; Belongs to the CbiM family.
 
  
  0.667
lex1
Lipooligosaccharide biosynthesis protein; Involved in extracellular lipooligosaccharide (LOS) biosynthesis and virulence expression. Involved in the synthesis of the oligosaccharide moiety of the LOS molecule by adding GalNAc; Belongs to the glycosyltransferase 25 family.
  
     0.650
HI_0461
Conserved hypothetical protein; Similar to SP:P32181 percent identity: 35.64; identified by sequence similarity; putative.
  
     0.633
iga
Immunoglobin A1 protease (iga1); Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments.
  
     0.632
HI_1680
Conserved hypothetical transmembrane protein; Similar to GB:U00096 PID:1787194 percent identity: 38.90; identified by sequence similarity; putative.
  
     0.622
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.