node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HI_0028 | HI_0431 | HI_0028 | HI_0431 | Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family. | Conserved hypothetical protein; Similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 percent identity: 54.59; identified by sequence similarity; putative; To E.coli YjaG. | 0.481 |
HI_0028 | HI_1205 | HI_0028 | HI_1205 | Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family. | Conserved hypothetical protein; Similar to GB:U00096 PID:1788632 GB:U00096 PID:1788632 percent identity: 45.45; identified by sequence similarity; putative. | 0.767 |
HI_0028 | fadR | HI_0028 | HI_0426 | Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family. | Fatty acid metabolism regulator protein (fadR); Multifunctional regulator of fatty acid metabolism. | 0.742 |
HI_0028 | metJ | HI_0028 | HI_0294 | Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family. | Met repressor (metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.770 |
HI_0028 | mutH | HI_0028 | HI_0403 | Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family. | DNA mismatch repair protein (mutH); Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. | 0.753 |
HI_0028 | nlpI | HI_0028 | HI_0230 | Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family. | Conserved hypothetical protein; May be involved in cell division. | 0.765 |
HI_0028 | proQ | HI_0028 | HI_1670 | Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family. | Predicted coding region HI1670; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.754 |
HI_0028 | rraB | HI_0028 | HI_0700 | Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family. | Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.773 |
HI_0028 | rseA | HI_0028 | HI_0629 | Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family. | sigma-E factor negative regulatory protein (mclA); An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytopl [...] | 0.745 |
HI_0028 | seqA | HI_0028 | HI_0192 | Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family. | seqA protein (seqA); Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.763 |
HI_0431 | HI_0028 | HI_0431 | HI_0028 | Conserved hypothetical protein; Similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 percent identity: 54.59; identified by sequence similarity; putative; To E.coli YjaG. | Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family. | 0.481 |
HI_0431 | HI_1205 | HI_0431 | HI_1205 | Conserved hypothetical protein; Similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 percent identity: 54.59; identified by sequence similarity; putative; To E.coli YjaG. | Conserved hypothetical protein; Similar to GB:U00096 PID:1788632 GB:U00096 PID:1788632 percent identity: 45.45; identified by sequence similarity; putative. | 0.602 |
HI_0431 | metJ | HI_0431 | HI_0294 | Conserved hypothetical protein; Similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 percent identity: 54.59; identified by sequence similarity; putative; To E.coli YjaG. | Met repressor (metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.525 |
HI_0431 | mutH | HI_0431 | HI_0403 | Conserved hypothetical protein; Similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 percent identity: 54.59; identified by sequence similarity; putative; To E.coli YjaG. | DNA mismatch repair protein (mutH); Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. | 0.400 |
HI_0431 | nlpI | HI_0431 | HI_0230 | Conserved hypothetical protein; Similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 percent identity: 54.59; identified by sequence similarity; putative; To E.coli YjaG. | Conserved hypothetical protein; May be involved in cell division. | 0.603 |
HI_0431 | proQ | HI_0431 | HI_1670 | Conserved hypothetical protein; Similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 percent identity: 54.59; identified by sequence similarity; putative; To E.coli YjaG. | Predicted coding region HI1670; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.724 |
HI_0431 | rraB | HI_0431 | HI_0700 | Conserved hypothetical protein; Similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 percent identity: 54.59; identified by sequence similarity; putative; To E.coli YjaG. | Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.667 |
HI_0431 | rseA | HI_0431 | HI_0629 | Conserved hypothetical protein; Similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 percent identity: 54.59; identified by sequence similarity; putative; To E.coli YjaG. | sigma-E factor negative regulatory protein (mclA); An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytopl [...] | 0.739 |
HI_0431 | seqA | HI_0431 | HI_0192 | Conserved hypothetical protein; Similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 percent identity: 54.59; identified by sequence similarity; putative; To E.coli YjaG. | seqA protein (seqA); Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.639 |
HI_1205 | HI_0028 | HI_1205 | HI_0028 | Conserved hypothetical protein; Similar to GB:U00096 PID:1788632 GB:U00096 PID:1788632 percent identity: 45.45; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548 percent identity: 50.59; identified by sequence similarity; putative; Belongs to the UPF0250 family. | 0.767 |