Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HI_0035Conserved hypothetical protein; Similar to GB:L10328 SP:P29211 GB:M94104 PID:290534 PID:147371 percent identity: 63.41; identified by sequence similarity; putative. (551 aa)    
Predicted Functional Partners:
glpB
Anaerobic glycerol-3-phosphate dehydrogenase, subunit B (glpB); Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor (By similarity).
  
     0.569
dcuB
Anaerobic C4-dicarboxylate membrane transporter protein (dcuB); Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
  
     0.554
frdD
Fumarate reductase, 13 kDa hydrophobic protein (frdD); Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
  
     0.531
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
       0.499
HI_0036
ABC transporter, ATP-binding protein; Similar to SP:Q50614 PID:1483552 percent identity: 42.52; identified by sequence similarity; putative.
       0.490
HI_0108
Conserved hypothetical protein; Similar to GB:U14003 SP:P39402 PID:537207 GB:U00096 PID:1790826 percent identity: 39.25; identified by sequence similarity; putative.
 
     0.490
frdC
Fumarate reductase, 15 kDa hydrophobic protein (frdC); Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
  
     0.474
glpC
Anaerobic glycerol-3-phosphate dehydrogenase, subunit C (glpC); Electron transfer protein; may also function as the membrane anchor for the GlpAB dimer.
  
     0.469
mrdA
Penicillin-binding protein 2 (pbp2); Catalyzes cross-linking of the peptidoglycan cell wall.
 
     0.457
rlmH
Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
       0.406
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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