Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HI_0040Conserved hypothetical protein; Similar to PID:1944176 percent identity: 47.58; identified by sequence similarity; putative. (258 aa)    
Predicted Functional Partners:
xthA
Exodeoxyribonuclease III (xthA); Major apurinic-apyrimidinic endonuclease of E.coli. It removes the damaged DNA at cytosines and guanines by cleaving on the 3'-side of the AP site by a beta-elimination reaction (By similarity). Belongs to the DNA repair enzymes AP/ExoA family.
       0.825
HI_0042
Conserved hypothetical protein; Similar to SP:P39219 GB:U00096 PID:1786244 percent identity: 34.95; identified by sequence similarity; putative.
       0.625
HI_0043
Conserved hypothetical transmembrane protein; Similar to SP:P45525 GB:U00096 PID:1787582 percent identity: 42.69; identified by sequence similarity; putative.
       0.625
rpsI
Ribosomal protein S9 (rpS9); Similar to GB:S75161 SP:P31782 PID:241867 percent identity: 94.62; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS9 family.
    
   0.542
HI_0044
Conserved hypothetical transmembrane protein; Similar to SP:P06967 GB:X00547 PID:41284 GB:U00096 PID:1787205 percent identity: 61.47; identified by sequence similarity; putative.
       0.489
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.