STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HI_0043Conserved hypothetical transmembrane protein; Similar to SP:P45525 GB:U00096 PID:1787582 percent identity: 42.69; identified by sequence similarity; putative. (354 aa)    
Predicted Functional Partners:
HI_1637
Conserved hypothetical protein; Similar to GB:U00096 PID:1787581 percent identity: 50.00; identified by sequence similarity; putative; To E.coli YcjX.
 
  
 0.973
HI_0042
Conserved hypothetical protein; Similar to SP:P39219 GB:U00096 PID:1786244 percent identity: 34.95; identified by sequence similarity; putative.
       0.773
HI_0431
Conserved hypothetical protein; Similar to SP:P32680 PID:396338 GB:U00096 PID:1790432 percent identity: 54.59; identified by sequence similarity; putative; To E.coli YjaG.
  
     0.696
HI_0040
Conserved hypothetical protein; Similar to PID:1944176 percent identity: 47.58; identified by sequence similarity; putative.
       0.625
xthA
Exodeoxyribonuclease III (xthA); Major apurinic-apyrimidinic endonuclease of E.coli. It removes the damaged DNA at cytosines and guanines by cleaving on the 3'-side of the AP site by a beta-elimination reaction (By similarity). Belongs to the DNA repair enzymes AP/ExoA family.
       0.625
HI_0044
Conserved hypothetical transmembrane protein; Similar to SP:P06967 GB:X00547 PID:41284 GB:U00096 PID:1787205 percent identity: 61.47; identified by sequence similarity; putative.
       0.596
mepA
Penicillin-insensitive murein endopeptidase (mepA); Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.
  
     0.575
HI_1159
Conserved hypothetical protein; Similar to GB:U00096 SP:P77395 PID:1773174 PID:1786700 percent identity: 50.89; identified by sequence similarity; putative.
  
    0.497
zapB
Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
     0.470
arfA
Conserved hypothetical protein; Rescues ribosomes stalled at the 3' end of non-stop mRNAs. Recruits release factor 2 (RF2) to the stalled ribosome, helping position it correctly in the ribosomal A site so its GGQ motif can hydrolyze the peptidyl-tRNA bond (By similarity).
  
     0.469
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.