Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uxuAMannonate dehydratase (uxuA); Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family. (394 aa)    
Predicted Functional Partners:
kdgK
2-dehydro-3-deoxygluconokinase (kdgK); Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG).
 
  
 0.992
HI_0048
Oxidoreductase; Similar to GB:AL009126 percent identity: 48.39; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.944
rpiA
Ribose 5-phosphate isomerase A (rpiA); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
 0.922
gnd
6-phosphogluconate dehydrogenase, decarboxylating (gnd); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
  0.920
rpe
Ribulose-phosphate 3-epimerase (dod); Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
     
  0.920
uxuR
Uxu operon regulator (uxuR); Repressor for the uxuRBA operon.
 
   
 0.832
HI_0053
Zinc-type alcohol dehydrogenase; Similar to GB:M96947 SP:Q06004 PID:304153 GB:AL009126 percent identity: 34.47; identified by sequence similarity; putative.
  
  
 0.785
eda
4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase (eda); Similar to GB:L20897 GB:M87458 GB:X63694 GB:X68871 PID:145827 percent identity: 37.31; identified by sequence similarity; putative; Belongs to the KHG/KDPG aldolase family.
 
  
 0.678
HI_0052
Conserved hypothetical protein; Similar to SP:P37676 PID:466717 GB:U00096 PID:1790004 percent identity: 27.19; identified by sequence similarity; putative.
     
 0.669
fabG
3-ketoacyl-acyl carrier protein reductase (fabG); Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.572
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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