Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
rec2Recombination protein (rec2); Might contribute to transformation as a member of a membrane- bound pore complex at the base of the transformasome. It could directly interact with transforming DNA during translocation indirectly by participating in the assembly of the pore. (788 aa)    
Predicted Functional Partners:
dprA
DNA processing chain A (dprA); Essential for efficient chromosomal DNA transformation but not required for plasmid transformation. Its disruption can be partially complemented by the smf gene of E.coli ; Belongs to the DprA/Smf family.
 
  
 0.916
comF
Competence protein F (comF); Involved in transformation (competence for DNA uptake).
 
  
 0.876
hofD
Type 4 prepilin-like protein specific leader peptidase (hopD); Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
  
 0.786
HI_1008
Conserved hypothetical protein; Similar to GB:U00096 SP:P77415 PID:1580713 PID:1773126 PID:1786646 percent identity: 37.04; identified by sequence similarity; putative.
 
  
 0.765
hofB
Protein transport protein; Similar to GB:M32066 SP:P22608 GB:S43866 PID:151065 percent identity: 41.16; identified by sequence similarity; putative; Belongs to the GSP E family.
 
  
 0.759
hofC
Protein transport protein; Similar to GB:M32066 SP:P22609 PID:151066 percent identity: 29.18; identified by sequence similarity; putative.
  
  
 0.758
msbA
ABC transporter, ATP-binding protein (msbA); Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
     
 0.750
HI_0938
Predicted coding region HI0938; Hypothetical protein; identified by GeneMark; putative.
  
  
 0.706
recA
recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Plays a central role in DNA metabolism, participating in general homologous recombination, recombinational (postreplication) DNA repair, and prophage induction; Belongs to the RecA family.
  
  
 0.694
HI_0952
DNA repair protein (radC); Similar to GB:L10328 SP:P25531 GB:X63366 GB:X63367 PID:290488 percent identity: 49.77; identified by sequence similarity; putative; Belongs to the UPF0758 family.
 
  
 0.686
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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