STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hflChflC protein (hflC); HflC and HflK could regulate a protease. (295 aa)    
Predicted Functional Partners:
hflK
hflK protein (hflK); HflC and HflK could encode or regulate a protease.
 
 
0.995
ftsH
Cell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.
   
 0.831
HI_1465
Cell division ftsH-related protein; Similar to GB:M83138 SP:P28691 GB:U01376 PID:146028 PID:606116 percent identity: 77.66; identified by sequence similarity; putative; In the C-terminal section; belongs to the peptidase M41 family.
   
 0.831
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase (trpX); Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
 
  
 0.608
pqqL
Zinc protease, putative; Similar to SP:P31828 GB:X71917 PID:535004 GB:U00096 PID:1742451 percent identity: 28.76; identified by sequence similarity; putative.
   
 0.606
yidC
Inner membrane protein, 60 kDa (yidC); Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
 
 0.532
HI_0152
Predicted coding region HI0152; May transfer the 4'-phosphopantetheine moiety from coenzyme A (CoA) to a serine residue of a carrier protein domain; Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
  
    0.520
atpA
ATP synthase F1, subunit alpha (atpA); Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 
 0.441
engB
Conserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
  
    0.440
psd
Phosphatidylserine decarboxylase proenzyme (psd); Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
    
   0.423
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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