Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HI_0184Esterase; Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate (By similarity). (275 aa)    
Predicted Functional Partners:
frmA
Alcohol dehydrogenase, class III (adhC); Similar to SP:P25437 PID:887431 GB:U00096 PID:1786552 PID:2443392 percent identity: 89.97; identified by sequence similarity; putative; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.999
fdxH
Formate dehydrogenase, beta subunit (fdxH); Allows to use formate as major electron donor during aerobic respiration. The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. Electrons are transferred from the gamma chain to the molybdenum cofactor of the alpha subunit (By similarity).
     
  0.920
fdxI
Formate dehydrogenase, gamma subunit (fdxI); Allows to use formate as major electron donor during anaerobic respiration. Subunit gamma is probably the cytochrome b556(FDO) component of the formate dehydrogenase (By similarity).
     
  0.920
HI_0183
Amino acid carrier protein, putative; Similar to PID:757741 SP:Q45068 PID:1405464 GB:AL009126 percent identity: 47.97; identified by sequence similarity; putative.
      
 0.618
bolA
Transcriptional regulator, putative (bolA); Transcriptional regulator that plays an important role in general stress response.
      
 0.540
HI_0186
Transcriptional regulator, putative; Similar to GB:D26185 SP:P37510 PID:467364 GB:AL009126 percent identity: 43.40; identified by sequence similarity; putative.
       0.536
HI_0053
Zinc-type alcohol dehydrogenase; Similar to GB:M96947 SP:Q06004 PID:304153 GB:AL009126 percent identity: 34.47; identified by sequence similarity; putative.
  
 
 0.490
nqrA
NADH:ubiquinone oxidoreducatase subunit A, Na translocating; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
      
 0.464
nagK
Sugar kinase, putative; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
      
 0.450
ddh
D-lactate dehydrogenase, fermentative (ldhA); Similar to PID:1049265 SP:P52643 GB:U00096 PID:1742253 PID:1742259 percent identity: 70.86; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
  0.442
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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