node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fldA | fur | HI_0191 | HI_0190 | Flavodoxin (fldA); Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | 0.782 |
fur | fldA | HI_0190 | HI_0191 | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | Flavodoxin (fldA); Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | 0.782 |
fur | iscA | HI_0190 | HI_0376 | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | Conserved hypothetical protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system (By similarity); Belongs to the HesB/IscA family. | 0.583 |
fur | katA | HI_0190 | HI_0928 | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | Catalase (hktE); Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; Belongs to the catalase family. | 0.523 |
fur | rpoA | HI_0190 | HI_0802 | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | DNA-directed RNA polymerase, alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.697 |
fur | rpoB | HI_0190 | HI_0515 | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | DNA-directed RNA polymerase, beta chain (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.621 |
fur | rpoC | HI_0190 | HI_0514 | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | DNA-directed RNA polymerase, beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.618 |
fur | rpoD | HI_0190 | HI_0533 | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | RNA polymerase sigma-70 factor (rpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.592 |
fur | rpoH | HI_0190 | HI_0269 | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | RNA polymerase sigma-32 factor (rpoH); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.591 |
fur | rpoZ | HI_0190 | HI_1742 | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | DNA-directed RNA polymerase, omega chain (rpoZ); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.618 |
fur | trxA | HI_0190 | HI_0084 | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | Thioredoxin (trxM); Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. | 0.585 |
iscA | fur | HI_0376 | HI_0190 | Conserved hypothetical protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system (By similarity); Belongs to the HesB/IscA family. | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | 0.583 |
katA | fur | HI_0928 | HI_0190 | Catalase (hktE); Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; Belongs to the catalase family. | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | 0.523 |
rpoA | fur | HI_0802 | HI_0190 | DNA-directed RNA polymerase, alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | 0.697 |
rpoA | rpoB | HI_0802 | HI_0515 | DNA-directed RNA polymerase, alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, beta chain (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
rpoA | rpoC | HI_0802 | HI_0514 | DNA-directed RNA polymerase, alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
rpoA | rpoD | HI_0802 | HI_0533 | DNA-directed RNA polymerase, alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase sigma-70 factor (rpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.999 |
rpoA | rpoH | HI_0802 | HI_0269 | DNA-directed RNA polymerase, alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase sigma-32 factor (rpoH); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.912 |
rpoA | rpoZ | HI_0802 | HI_1742 | DNA-directed RNA polymerase, alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, omega chain (rpoZ); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.999 |
rpoB | fur | HI_0515 | HI_0190 | DNA-directed RNA polymerase, beta chain (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Ferric uptake regulation protein (fur); Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | 0.621 |