Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HI_0193Esterase/lipase, putative; Similar to GB:U00096 PID:1786902 percent identity: 43.65; identified by sequence similarity; putative; Belongs to the DmpD/TodF/XylF esterase family. (287 aa)    
Predicted Functional Partners:
HI_0082
Predicted coding region HI0082; Hypothetical protein; identified by GeneMark; putative.
   
 0.848
acpP
Acyl carrier protein (acpP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
 
 
 0.726
menE
O-succinylbenzoate--CoA ligase (menE); Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
  
 0.718
seqA
seqA protein (seqA); Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
       0.647
apaH
Diadenosine-tetraphosphatase (apaH); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
  0.646
pta
Phosphate acetyltransferase (pta); Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.620
fldA
Flavodoxin (fldA); Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
       0.614
guaA
GMP synthase (guaA); Catalyzes the synthesis of GMP from XMP.
   
  0.611
atoD
Acetate CoA-transferase, alpha subunit; Similar to GB:U00096 SP:P76458 PID:1736876 PID:1788551 percent identity: 63.13; identified by sequence similarity; putative.
  
 
 0.610
aroC
Chorismate synthase (aroC); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
    
  0.602
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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