| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HI_0216 | HI_0217 | HI_0216 | HI_0217 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Conserved hypothetical protein; Similar to PID:984584 GB:U00096 SP:Q47152 PID:1552796 PID:1786422 percent identity: 48.05; identified by sequence similarity; putative; Belongs to the transposase 17 family. RAYT subfamily. | 0.499 |
| HI_0216 | HI_1285 | HI_0216 | HI_1285 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Type I restriction enzyme (hsdR); Subunit R is required for both nuclease and ATPase activities, but not for modification. | 0.684 |
| HI_0216 | HI_1286 | HI_0216 | HI_1286 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | 0.476 |
| HI_0216 | HI_1287 | HI_0216 | HI_1287 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities. | 0.970 |
| HI_0216 | rnpA | HI_0216 | HI_0999 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Ribonuclease P (rnpA); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.540 |
| HI_0216 | ruvB | HI_0216 | HI_0312 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Holliday junction DNA helicase (ruvB); The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.540 |
| HI_0216 | uvrB | HI_0216 | HI_1247 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Excinuclease ABC, subunit B (uvrB); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dis [...] | 0.540 |
| HI_0216 | uvrC | HI_0216 | HI_0057 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Excinuclease ABC, subunit C (uvrC); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.548 |
| HI_0216 | xerC | HI_0216 | HI_0676 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Integrase/recombinase (xerC); Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.540 |
| HI_0216 | xerD | HI_0216 | HI_0309 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Integrase/recombinase (xerD); Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.544 |
| HI_0217 | HI_0216 | HI_0217 | HI_0216 | Conserved hypothetical protein; Similar to PID:984584 GB:U00096 SP:Q47152 PID:1552796 PID:1786422 percent identity: 48.05; identified by sequence similarity; putative; Belongs to the transposase 17 family. RAYT subfamily. | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | 0.499 |
| HI_1285 | HI_0216 | HI_1285 | HI_0216 | Type I restriction enzyme (hsdR); Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | 0.684 |
| HI_1285 | HI_1286 | HI_1285 | HI_1286 | Type I restriction enzyme (hsdR); Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | 0.940 |
| HI_1285 | HI_1287 | HI_1285 | HI_1287 | Type I restriction enzyme (hsdR); Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities. | 0.969 |
| HI_1286 | HI_0216 | HI_1286 | HI_0216 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | 0.476 |
| HI_1286 | HI_1285 | HI_1286 | HI_1285 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Type I restriction enzyme (hsdR); Subunit R is required for both nuclease and ATPase activities, but not for modification. | 0.940 |
| HI_1286 | HI_1287 | HI_1286 | HI_1287 | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities. | 0.996 |
| HI_1287 | HI_0216 | HI_1287 | HI_0216 | Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities. | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | 0.970 |
| HI_1287 | HI_1285 | HI_1287 | HI_1285 | Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities. | Type I restriction enzyme (hsdR); Subunit R is required for both nuclease and ATPase activities, but not for modification. | 0.969 |
| HI_1287 | HI_1286 | HI_1287 | HI_1286 | Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities. | Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity). | 0.996 |
