Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HI_0217Conserved hypothetical protein; Similar to PID:984584 GB:U00096 SP:Q47152 PID:1552796 PID:1786422 percent identity: 48.05; identified by sequence similarity; putative; Belongs to the transposase 17 family. RAYT subfamily. (176 aa)    
Predicted Functional Partners:
HI_0216
Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).
       0.499
pheA
Chorismate mutase / prephenate dehydratase (pheA); Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
    
  0.402
ureC
Urease, alpha subunit (ureC); Similar to SP:Q07397 PID:216362 percent identity: 67.25; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
    
   0.400
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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