Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HI_0256Lipoprotein, putative; Similar to SP:P21167 PID:147409 PID:42126 GB:U00096 PID:1788822 percent identity: 28.37; identified by sequence similarity; putative. (215 aa)    
Predicted Functional Partners:
bamA
Protective surface antigen D15; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
   
 
 0.957
bamE
Small protein A, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
   
 
 0.925
bamD
Lipoprotein, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
    
 
 0.907
surA
Stationary phase survival protein SurA, putative; Chaperone involved in the folding of extracytoplasmic proteins.
   
 
 0.855
dapA
Dihydrodipicolinate synthetase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
    0.662
lptE
Rare lipoprotein B, putative; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.
   
 
 0.560
bcp
Bacterioferritin comigratory protein (bcp); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events; Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.
  
    0.532
ompA
Outer membrane protein P5 (ompA); With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
   
 
 0.485
ppiD
Peptidyl-prolyl cis-trans isomerse, putative; PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins (By similarity).
   
 
 0.479
yfiA
Sigma(54) modulation protein, putative; During stationary phase, prevents 70S dimer formation, probably in order to regulate translation efficiency during transition between the exponential and the stationary phases. In addition, during environmental stress such as cold shock or excessive cell density at stationary phase, stabilizes the 70S ribosome against dissociation, inhibits translation initiation and increase translation accuracy. When normal growth conditions are restored, is quickly released from the ribosome (By similarity); Belongs to the HPF/YfiA ribosome-associated protein [...]
       0.461
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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