Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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yfiASigma(54) modulation protein, putative; During stationary phase, prevents 70S dimer formation, probably in order to regulate translation efficiency during transition between the exponential and the stationary phases. In addition, during environmental stress such as cold shock or excessive cell density at stationary phase, stabilizes the 70S ribosome against dissociation, inhibits translation initiation and increase translation accuracy. When normal growth conditions are restored, is quickly released from the ribosome (By similarity); Belongs to the HPF/YfiA ribosome-associated protein [...] (107 aa)    
Predicted Functional Partners:
rpsF
Ribosomal protein S6 (rpS6); Binds together with S18 to 16S ribosomal RNA; Belongs to the bacterial ribosomal protein bS6 family.
    
 0.988
rpsI
Ribosomal protein S9 (rpS9); Similar to GB:S75161 SP:P31782 PID:241867 percent identity: 94.62; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS9 family.
   
 0.986
rpsR
Ribosomal protein S18 (rpS18); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
    
  0.985
rpsG
Ribosomal protein S7 (rpS7); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
  0.985
rpsS
Ribosomal protein S19 (rpS19); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
    
  0.985
rpsC
Ribosomal protein S3 (rpS3); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
    
  0.985
rpsQ
Ribosomal protein S17 (rpS17); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
    
  0.985
rpsH
Ribosomal protein S8 (rpS8); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
    
  0.985
rpsE
Ribosomal protein S5 (rpS5); With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
    
 0.985
rpsK
Ribosomal protein S11 (rpS11); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
    
  0.985
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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