HI_0281 protein (Haemophilus influenzae) - STRING interaction network

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HI_0281

Transport protein, putative; Similar to SP:P37643 PID:466660 GB:U00096 PID:1789941 percent identity: 55.42; identified by sequence similarity; putative. (438 aa)

Predicted Functional Partners:

menD

0.790

menF

0.784

menH

0.605

pheA

0.406

Your Current Organism:

Haemophilus influenzae

NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HI_0281	menD	HI_0281	HI_0283	Transport protein, putative; Similar to SP:P37643 PID:466660 GB:U00096 PID:1789941 percent identity: 55.42; identified by sequence similarity; putative.	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase/2-oxoglutarate decarboxylase (menD); Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).	0.790
HI_0281	menF	HI_0281	HI_0285	Transport protein, putative; Similar to SP:P37643 PID:466660 GB:U00096 PID:1789941 percent identity: 55.42; identified by sequence similarity; putative.	Menaquinone-specific isochorismate synthase (menF); Catalyzes the conversion of chorismate to isochorismate.	0.784
HI_0281	menH	HI_0281	HI_0282	Transport protein, putative; Similar to SP:P37643 PID:466660 GB:U00096 PID:1789941 percent identity: 55.42; identified by sequence similarity; putative.	Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).	0.605
HI_0281	pheA	HI_0281	HI_1145	Transport protein, putative; Similar to SP:P37643 PID:466660 GB:U00096 PID:1789941 percent identity: 55.42; identified by sequence similarity; putative.	Chorismate mutase / prephenate dehydratase (pheA); Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	0.406
menD	HI_0281	HI_0283	HI_0281	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase/2-oxoglutarate decarboxylase (menD); Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).	Transport protein, putative; Similar to SP:P37643 PID:466660 GB:U00096 PID:1789941 percent identity: 55.42; identified by sequence similarity; putative.	0.790
menD	menF	HI_0283	HI_0285	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase/2-oxoglutarate decarboxylase (menD); Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).	Menaquinone-specific isochorismate synthase (menF); Catalyzes the conversion of chorismate to isochorismate.	0.999
menD	menH	HI_0283	HI_0282	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase/2-oxoglutarate decarboxylase (menD); Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).	Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).	0.998
menF	HI_0281	HI_0285	HI_0281	Menaquinone-specific isochorismate synthase (menF); Catalyzes the conversion of chorismate to isochorismate.	Transport protein, putative; Similar to SP:P37643 PID:466660 GB:U00096 PID:1789941 percent identity: 55.42; identified by sequence similarity; putative.	0.784
menF	menD	HI_0285	HI_0283	Menaquinone-specific isochorismate synthase (menF); Catalyzes the conversion of chorismate to isochorismate.	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase/2-oxoglutarate decarboxylase (menD); Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).	0.999
menF	menH	HI_0285	HI_0282	Menaquinone-specific isochorismate synthase (menF); Catalyzes the conversion of chorismate to isochorismate.	Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).	0.883
menF	pheA	HI_0285	HI_1145	Menaquinone-specific isochorismate synthase (menF); Catalyzes the conversion of chorismate to isochorismate.	Chorismate mutase / prephenate dehydratase (pheA); Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	0.971
menH	HI_0281	HI_0282	HI_0281	Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).	Transport protein, putative; Similar to SP:P37643 PID:466660 GB:U00096 PID:1789941 percent identity: 55.42; identified by sequence similarity; putative.	0.605
menH	menD	HI_0282	HI_0283	Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase/2-oxoglutarate decarboxylase (menD); Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).	0.998
menH	menF	HI_0282	HI_0285	Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).	Menaquinone-specific isochorismate synthase (menF); Catalyzes the conversion of chorismate to isochorismate.	0.883
menH	pheA	HI_0282	HI_1145	Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).	Chorismate mutase / prephenate dehydratase (pheA); Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	0.564
pheA	HI_0281	HI_1145	HI_0281	Chorismate mutase / prephenate dehydratase (pheA); Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	Transport protein, putative; Similar to SP:P37643 PID:466660 GB:U00096 PID:1789941 percent identity: 55.42; identified by sequence similarity; putative.	0.406
pheA	menF	HI_1145	HI_0285	Chorismate mutase / prephenate dehydratase (pheA); Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	Menaquinone-specific isochorismate synthase (menF); Catalyzes the conversion of chorismate to isochorismate.	0.971
pheA	menH	HI_1145	HI_0282	Chorismate mutase / prephenate dehydratase (pheA); Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).	0.564

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