STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HI_0293Transcriptional regulator, merR family, putative; Could be a copper-dependent transcriptional activator of the ATPase HI_0290. (128 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase sigma-70 factor (rpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.827
HI_0292
Mercuric ion scavenger protein (merP); Similar to GB:X73112 PID:483769 SP:Q51770 percent identity: 32.84; identified by sequence similarity; putative.
  
  
 0.669
HI_0290
Potassium/copper-transporting ATPase, putative; Similar to GB:AL009126 percent identity: 39.57; identified by sequence similarity; putative; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
  
  
 0.625
rpoC
DNA-directed RNA polymerase, beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.610
rpoB
DNA-directed RNA polymerase, beta chain (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.610
rpoA
DNA-directed RNA polymerase, alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.610
rpoZ
DNA-directed RNA polymerase, omega chain (rpoZ); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
    
   0.610
HI_0291
Predicted coding region HI0291; Hypothetical protein; identified by GeneMark; putative.
  
  
 0.569
maeB
Malate oxidoreductase, putative; Similar to GB:U00096 PID:1788806 PID:1799885 PID:1799887 percent identity: 68.69; identified by sequence similarity; putative; In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
    
  0.540
HI_0186
Transcriptional regulator, putative; Similar to GB:D26185 SP:P37510 PID:467364 GB:AL009126 percent identity: 43.40; identified by sequence similarity; putative.
  
 
   0.529
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
Server load: low (28%) [HD]