STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hofDType 4 prepilin-like protein specific leader peptidase (hopD); Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (230 aa)    
Predicted Functional Partners:
hofC
Protein transport protein; Similar to GB:M32066 SP:P22609 PID:151066 percent identity: 29.18; identified by sequence similarity; putative.
 
  
 0.975
hofB
Protein transport protein; Similar to GB:M32066 SP:P22608 GB:S43866 PID:151065 percent identity: 41.16; identified by sequence similarity; putative; Belongs to the GSP E family.
  
 
 0.924
ppdD
Prepilin peptidase dependent protein D; Similar to GB:D26562 SP:P36647 GB:L28105 PID:473777 PID:456042 percent identity: 41.54; identified by sequence similarity; putative.
 
   
 0.874
rec2
Recombination protein (rec2); Might contribute to transformation as a member of a membrane- bound pore complex at the base of the transformasome. It could directly interact with transforming DNA during translocation indirectly by participating in the assembly of the pore.
  
  
 0.786
dprA
DNA processing chain A (dprA); Essential for efficient chromosomal DNA transformation but not required for plasmid transformation. Its disruption can be partially complemented by the smf gene of E.coli ; Belongs to the DprA/Smf family.
  
  
 0.683
ampD
ampD signalling protein (ampD); Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
     
 0.622
comE
Competence protein E (comE); Involved in transformation (competence for DNA uptake); Belongs to the bacterial secretin family. PilQ subfamily.
 
  
 0.573
HI_1008
Conserved hypothetical protein; Similar to GB:U00096 SP:P77415 PID:1580713 PID:1773126 PID:1786646 percent identity: 37.04; identified by sequence similarity; putative.
   
  
 0.567
HI_0938
Predicted coding region HI0938; Hypothetical protein; identified by GeneMark; putative.
  
  
 0.525
HI_1399
Predicted coding region HI1399; Hypothetical protein; identified by GeneMark; putative.
  
     0.517
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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